John Kingdom, MD, FRCSC, FCAHS

Print Friendly, PDF & Email

Dr. Kingdom is a High-Risk Obstetrician and Maternal-Fetal Medicine subspecialist with a clinical and research focus on placenta-mediated pregnancy complications, including the assessment and surgical management of patients at risk of placenta accreta spectrum disorder (PAS) via the Placenta Clinic. Since 2017, the program has incorporated real-time maternal Placenta Growth Factor (PlGF) testing into screening, diagnosis and management decisions, and forms a major part of current research themes. The group has just completed a PlGF screening study with GDM testing at 24-28 weeks to predict early preterm delivery. His research with advanced imaging methods is connected with the Departments of Medical Biophysics and Pediatric Cardiology at SickKids and Medical Imaging and Placental-Perinatal Pathology at UHN-Sinai. His pathology research interests focus on developing disease-specific care pathways. His basic science research focus is to support the laboratory research program of Dr. Sascha Drewlo at Sunnybrook Health Sciences Centre that focuses on analysis of placenta-derived trophoblast cells that are naturally shed into the cervical canal during early pregnancy development. Their current research focus is on heparin-mediated restoration of deficient circulating PlGF in the early second trimester. Dr. Kingdom is cross-appointed to the graduate Department of Laboratory Medicine and Pathobiology. His research is currently funded by the Canadian Institutes of Health Research (since 2003), the National Institutes of Health, USA, the AMO-Innovation Fund at Sinai-UHN, and several grateful donors. He has previously been funded by the Ontario Physicians’ Services Incorporated Foundation and the Alva Foundation. Dr. Kingdom is the past Chair of the Department of Obstetrics & Gynaecology at the University of Toronto (2013-2023). Through his ongoing research interests, he continues his dual passions helping postgraduate trainees to enjoy participation in team-based research, and in providing advice and support to new faculty members in their early career development.